rs4444235
| Orientation | plus |
| Stabilized | plus |
| Make rs4444235(C;C) |
| Make rs4444235(C;T) |
| Make rs4444235(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 14 |
| Position | 53944201 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4444235 |
| dbSNP (classic) | rs4444235 |
| ClinGen | rs4444235 |
| ebi | rs4444235 |
| HLI | rs4444235 |
| Exac | rs4444235 |
| Gnomad | rs4444235 |
| Varsome | rs4444235 |
| LitVar | rs4444235 |
| Map | rs4444235 |
| PheGenI | rs4444235 |
| Biobank | rs4444235 |
| 1000 genomes | rs4444235 |
| hgdp | rs4444235 |
| ensembl | rs4444235 |
| geneview | rs4444235 |
| scholar | rs4444235 |
| rs4444235 | |
| pharmgkb | rs4444235 |
| gwascentral | rs4444235 |
| openSNP | rs4444235 |
| 23andMe | rs4444235 |
| SNPshot | rs4444235 |
| SNPdbe | rs4444235 |
| MSV3d | rs4444235 |
| GWAS Ctlg | rs4444235 |
| GMAF | 0.4353 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs4444235, BMP4; P = 8.1 times 10-10)
| GWAS snp | |
|---|---|
| PMID | [PMID 19011631 ]
|
| Trait | Colorectal cancer |
| Title | Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer |
| Risk Allele | C |
| P-val | 8E-10 |
| Odds Ratio | 1.11 [1.08-1.15] |
[PMID 21119214] Colorectal Cancer Susceptibility Loci in a Population-Based Study: Associations with Morphological Parameters
[PMID 22367214] Characterization of gene-environment interactions for colorectal cancer susceptibility loci
[PMID 22363440] cis-Expression QTL Analysis of Established Colorectal Cancer Risk Variants in Colon Tumors and Adjacent Normal Tissue
[PMID 17847004] Common variants in the BMP2, BMP4, and HJV genes of the hepcidin regulation pathway modulate HFE hemochromatosis penetrance.
[PMID 19639606] Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.
[PMID 20501757] Low-penetrance susceptibility variants in familial colorectal cancer.
[PMID 20648012] Association studies on 11 published colorectal cancer risk loci.
[PMID 21071539] Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations.
[PMID 21314996] Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci.
[PMID 22045029] Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients.
[PMID 22158048] The 14q22.2 colorectal cancer variant rs4444235 shows cis-acting regulation of BMP4.
[PMID 22170598] Bone morphogenetic protein-4 polymorphism and colorectal cancer risk: a meta analysis.
[PMID 22235025] Susceptibility genetic variants associated with early-onset colorectal cancer.
[PMID 23359760] Single-nucleotide polymorphism associations for colorectal cancer in southern chinese population
[PMID 22848671] Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.
[PMID 22999960] Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.
[PMID 23161572] BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations.
[PMID 23434150] Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?
[PMID 24854447] Association analysis of colorectal cancer susceptibility variants with gastric cancer in a Chinese Han population
[PMID 24978480] A Colorectal Cancer Susceptibility New Variant at 4q26 in the Spanish Population Identified by Genome-Wide Association Analysis
[PMID 25647270] Common genetic variant on BMP4 contributes to colorectal adenoma and cancer: A meta-analysis based on 15 studies
[PMID 25710502] A Retrospective Observational Study of the Relationship between Single Nucleotide Polymorphisms Associated with the Risk of Developing Colorectal Cancer and Survival
[PMID 26078566] Association of colorectal cancer susceptibility variants with esophageal cancer in a Chinese population
[PMID 28849422] The more from East-Asian, the better: risk prediction of colorectal cancer risk by GWAS-identified SNPs among Japanese.
[PMID 31849324] Evaluation of gene-environment interactions for colorectal cancer susceptibility loci using case-only and case-control designs.
