rs4505848

Orientation

plus

Stabilized

plus

Make rs4505848(A;A)

Make rs4505848(A;G)

Make rs4505848(G;G)

Reference

GRCh38 38.1/141

Chromosome

4

Position

122211337

Gene

KIAA1109

is a	snp
is	mentioned by
dbSNP	rs4505848
dbSNP (classic)	rs4505848
ClinGen	rs4505848
ebi	rs4505848
HLI	rs4505848
Exac	rs4505848
Gnomad	rs4505848
Varsome	rs4505848
LitVar	rs4505848
Map	rs4505848
PheGenI	rs4505848
Biobank	rs4505848
1000 genomes	rs4505848
hgdp	rs4505848
ensembl	rs4505848
geneview	rs4505848
scholar	rs4505848
google	rs4505848
pharmgkb	rs4505848
gwascentral	rs4505848
openSNP	rs4505848
23andMe	rs4505848
SNPshot	rs4505848
SNPdbe	rs4505848
MSV3d	rs4505848
GWAS Ctlg	rs4505848

GMAF

0.3356

Max Magnitude

0

?	(A;A) (A;G) (G;G)	28

[PMID 19302705] Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study.

GWAS snp
PMID	[PMID 19430480]
Trait	Type 1 diabetes
Title	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
Risk Allele
P-val	5E-13
Odds Ratio	NR NR

OMIM	611598
Desc	CELIAC DISEASE, SUSCEPTIBILITY TO, 6; CELIAC6
Variant
Related	also

[PMID 22065918] CFH 184G as a genetic risk marker for anterior uveitis in Chinese females

[PMID 17558408] A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.

[PMID 17999365] Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases.

[PMID 20553587] Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.

[PMID 25661663] Association of 32 type 1 diabetes risk loci in Pakistani patients