rs4613763 increases susceptibility to Crohn's disease 1.56 times for carriers of the C allele [PMID 17447842
]
| GWAS snp
|
| PMID
|
[PMID 18587394]
|
| Trait
|
Crohn's disease
|
| Title
|
Genome-wide assocation defines more than 30 distinct susceptibility loci for Crohn's disease
|
| Risk Allele
|
C
|
| P-val
|
7.0000000000000003E-27
|
| Odds Ratio
|
1.32 [NR]
|
| OMIM | 612261 |
| Desc | INFLAMMATORY BOWEL DISEASE 17; IBD17 |
| Variant | |
| Related | also |
| OMIM | 612262 |
| Desc | INFLAMMATORY BOWEL DISEASE 18; IBD18 |
| Variant | |
| Related | also |
[PMID 20222910] Susceptibility loci reported in genome-wide association studies are associated with Crohn's disease in Canadian children
[PMID 17068223] A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.
[PMID 20018022] Replication of recently identified associated single-nucleotide polymorphisms from six autoimmune diseases in Genetic Analysis Workshop 16 rheumatoid arthritis data.
[PMID 21304977] An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.
| GWAS snp
|
| PMID
|
[PMID 21833088]
|
| Trait
|
Multiple sclerosis
|
| Title
|
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
|
| Risk Allele
|
G
|
| P-val
|
3E-16
|
| Odds Ratio
|
1.20 [1.18-1.22]
|
]
