A genome-wide association study using DNA samples from 1,052 individuals with ulcerative colitis and preexisting data from 2,571 controls, all of European ancestry, concluded that this SNP and several others were associated with altered risk for the disease.[PMID 19122664
]
| GWAS snp
|
| PMID
|
[PMID 19915572]
|
| Trait
|
Ulcerative colitis
|
| Title
|
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
|
| Risk Allele
|
|
| P-val
|
2E-11
|
| Odds Ratio
|
NR NR
|
| GWAS snp
|
| PMID
|
[PMID 21297633]
|
| Trait
|
|
| Title
|
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
|
| Risk Allele
|
A
|
| P-val
|
4E-35
|
| Odds Ratio
|
1.3000 [1.25-1.35]
|
[PMID 21304977] An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.
| GWAS snp
|
| PMID
|
[PMID 23128233]
|
| Trait
|
Ulcerative colitis
|
| Title
|
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
|
| Risk Allele
|
A
|
| P-val
|
2E-68
|
| Odds Ratio
|
1.27 [1.221-1.31]
|
]
