rs6604026

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(C;C)	2	>1.15x risk of multiple sclerosis
(C;T)	1.5	1.15x risk of multiple sclerosis
(T;T)	0	common

Reference

GRCh38 38.1/141

Chromosome

1

Position

92838046

Gene	FAM69A, RPL5

is a	snp
is	mentioned by
dbSNP	rs6604026
dbSNP (classic)	rs6604026
ClinGen	rs6604026
ebi	rs6604026
HLI	rs6604026
Exac	rs6604026
Gnomad	rs6604026
Varsome	rs6604026
LitVar	rs6604026
Map	rs6604026
PheGenI	rs6604026
Biobank	rs6604026
1000 genomes	rs6604026
hgdp	rs6604026
ensembl	rs6604026
geneview	rs6604026
scholar	rs6604026
google	rs6604026
pharmgkb	rs6604026
gwascentral	rs6604026
openSNP	rs6604026
23andMe	rs6604026
SNPshot	rs6604026
SNPdbe	rs6604026
MSV3d	rs6604026
GWAS Ctlg	rs6604026

GMAF

0.2167

Max Magnitude

2

?	(C;C) (C;T) (T;T)	28

rs6604026 has been reported in a large study to be associated with multiple sclerosis.

The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with this allele is 1.15 (CI 1.08-1.22). [PMID 17660530]

GWAS
SNP	rs6604026
PubMedID	[PMID 17660530]
Condition	Multiple sclerosis
Gene	RPL5
Risk Allele	C
pValue	8.00E-006
OR	1.15
95% CI	1.08-1.22

GWAS snp
PMID	[PMID 19525955]
Trait	Multiple sclerosis
Title	Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
Risk Allele	G
P-val	0.000003
Odds Ratio	1.17 [NR]

[PMID 18650830] Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in Australians

[PMID 20368992] Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients.

[PMID 20405052] The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.