rs727153
From SNPedia
Orientation | minus |
Stabilized | minus |
Make rs727153(A;A) |
Make rs727153(A;G) |
Make rs727153(G;G) |
Reference | GRCh38 38.1/141 |
Chromosome | 4 |
Position | 154733269 |
Gene | LRAT |
is a | snp |
is | mentioned by |
dbSNP | rs727153 |
dbSNP (classic) | rs727153 |
ClinGen | rs727153 |
ebi | rs727153 |
HLI | rs727153 |
Exac | rs727153 |
Gnomad | rs727153 |
Varsome | rs727153 |
LitVar | rs727153 |
Map | rs727153 |
PheGenI | rs727153 |
Biobank | rs727153 |
1000 genomes | rs727153 |
hgdp | rs727153 |
ensembl | rs727153 |
geneview | rs727153 |
scholar | rs727153 |
rs727153 | |
pharmgkb | rs727153 |
gwascentral | rs727153 |
openSNP | rs727153 |
23andMe | rs727153 |
SNPshot | rs727153 |
SNPdbe | rs727153 |
MSV3d | rs727153 |
GWAS Ctlg | rs727153 |
GMAF | 0.326 |
Max Magnitude | 0 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
GWAS snp | |
---|---|
PMID | [PMID 18823527] |
Trait | Alzheimer's disease |
Title | A genome-wide association study for late-onset Alzheimer's disease using DNA pooling |
Risk Allele | C |
P-val | 0.0000030000000000000001 |
Odds Ratio | 1.63 [1.37-1.95] |
This SNP is near the gene for lecithin retinol acyltransferase (phosphatidylcholine-retinol O-acetyltransferase) or LRAT, which is involved in Vitamin A metabolism; the risk allele is reportedly G (in dbSNP orientation). [PMID 18823527]
[PMID 20574532] Intermediate phenotypes identify divergent pathways to Alzheimer's disease.