Alzheimer's disease associated, based on large 2011 study 10.1038/ng.801
[PMID 21460841] Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
[PMID 19734902] Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
[PMID 21379329] Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
[PMID 21390209] Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.
GWAS snp
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PMID
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[PMID 22832961]
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Trait
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Title
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Genome-wide association study of Alzheimer's disease.
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Risk Allele
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P-val
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6E-11
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Odds Ratio
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1.2500 None
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[PMID 24260488] Epistatic Genetic Effects among Alzheimer's Candidate Genes
[PMID 23232270] Association of GWAS-linked loci with late-onset Alzheimer's disease in a northern Han Chinese population.
[PMID 20558387] Genetic variation and neuroimaging measures in Alzheimer disease.
[PMID 28302384] The bridging integrator 1 Gene rs7561528 polymorphism contributes to Alzheimer's disease susceptibility in East Asian and Caucasian populations.