rs7696175

Orientation

plus

Stabilized

plus

Make rs7696175(C;C)

Make rs7696175(C;T)

Make rs7696175(T;T)

Reference

GRCh38 38.1/141

Chromosome

4

Position

38819365

is a	snp
is	mentioned by
dbSNP	rs7696175
dbSNP (classic)	rs7696175
ClinGen	rs7696175
ebi	rs7696175
HLI	rs7696175
Exac	rs7696175
Gnomad	rs7696175
Varsome	rs7696175
LitVar	rs7696175
Map	rs7696175
PheGenI	rs7696175
Biobank	rs7696175
1000 genomes	rs7696175
hgdp	rs7696175
ensembl	rs7696175
geneview	rs7696175
scholar	rs7696175
google	rs7696175
pharmgkb	rs7696175
gwascentral	rs7696175
openSNP	rs7696175
23andMe	rs7696175
SNPshot	rs7696175
SNPdbe	rs7696175
MSV3d	rs7696175
GWAS Ctlg	rs7696175

GMAF

0.2608

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

rs7696175 in the TLR1, TLR6 loci;

Breast Cancer Risk

[PMID 22965832] For Southern Chinese: Variants of rs7696175/TLR1, TLR6, rs13281615/8q24, and rs16886165/MAP3K1 were also associated with increased breast cancer risk, with per-allele ORs (95 % CI) of 1.16 (1.00–1.34), 1.15 (1.02–1.29), and 1.15 (1.01–1.29), respectively.

[PMID 23563089] For Hispanic: Three of the five significant variants (rs17157903-RELN, rs7696175-TLR1 and rs13387042-2q35) were associated with risk among Hispanics but not in Non Hispanic Whites.

References:

[PMID 22965832] Chan et al, 2012 http://link.springer.com/article/10.1007%2Fs10549-012-2234-y

[PMID 23563089] Fejerman et al, 2013

[PMID 19619313] An assessment of the portability of ancestry informative markers between human populations.

[PMID 19639606] Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.

[PMID 20200442] Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.

[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.