rs9379896
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs9379896(C;C) |
| Make rs9379896(C;T) |
| Make rs9379896(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 10886716 |
| Gene | SYCP2L |
| is a | snp |
| is | mentioned by |
| dbSNP | rs9379896 |
| dbSNP (classic) | rs9379896 |
| ClinGen | rs9379896 |
| ebi | rs9379896 |
| HLI | rs9379896 |
| Exac | rs9379896 |
| Gnomad | rs9379896 |
| Varsome | rs9379896 |
| LitVar | rs9379896 |
| Map | rs9379896 |
| PheGenI | rs9379896 |
| Biobank | rs9379896 |
| 1000 genomes | rs9379896 |
| hgdp | rs9379896 |
| ensembl | rs9379896 |
| geneview | rs9379896 |
| scholar | rs9379896 |
| rs9379896 | |
| pharmgkb | rs9379896 |
| gwascentral | rs9379896 |
| openSNP | rs9379896 |
| 23andMe | rs9379896 |
| SNPshot | rs9379896 |
| SNPdbe | rs9379896 |
| MSV3d | rs9379896 |
| GWAS Ctlg | rs9379896 |
| GMAF | 0.2227 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs9379896 is a SNP on chromosome 6.
A case control study of ~2,000 women found that each rs9379896(C) allele was associated with an average increase in age at menopause of ~1 month. This also meant that each rs9379896(T) allele yielded an odds ratio of 1.13 (CI: 1.01–1.27, p = 3.8 x 10e-2) of early menopause, defined as occurring before the age of 46.[PMID 20952801
]
Overall, women homozygous for the "early" alleles at all 4 SNPs found in this study were ~4 times more likely to undergo menopause early compared to women who had a total of 3 or less risk alleles. However, the ability to predict which women will actually undergo early menopause using these 4 SNPs is still low.[PMID 20952801]
