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(Redirected from Brain Aneurysm)

An aneurysm is a localized ballooning in an artery due to a weak portion of the vessel wall. A ruptured aneurysm can cause hemorrhaging that is severely debilitating or fatal. The two most medically significant aneuryms occur at the base of the brain (intracranial aneurysms) and in the artery coming out of the heart (aortic aneurysms) Wikipedia. The most common type of aortic aneurysm is abdominal aortic aneurysm (AAA). Wikipedia

In 2014, a study found novel region on chromosome 7, near HDAC9, was associated with IA (rs10230207; P=4.14×10−8). See Stroke Journal 2014;45:3194-3199

In 2013, a meta-analysis confirmed 4 loci with robust association after random effects / sensitivity analysis. rs700651, rs9298506, rs10958409 and rs1333040. PMC3716358

As of 2010, at least 6 gene regions are known to be associated with increased risk for intracranial aneurysms in multiple ethnic groups, usually with multiple SNPs per region. [PMID 20364137], 23andMe blog