Frontotemporal dementia

At a minimum, these SNPs are known to be related, and others may also be

	Max Magnitude
rs193026789	7
rs36098294	0
rs5848	3
rs606231220	7
rs606231221	7
rs63749801	0
rs63749817	0
rs63749877	0
rs63750077	0
rs63750092	0
rs63750331	0
rs63750349	0
rs63750376	0
rs63750424	7
rs63750570	0
rs63750711	0
rs63750756	0
rs63750912	0
rs63750959	0
rs63750972	0
rs63751006	0
rs63751165	0
rs63751243	3.8
rs63751273	0
rs63751294	0
rs63751399	7
rs63751438	0
rs794729669	7
rs794729670	7
rs794729671	7
rs794729672	7

Known genetic loci according to "The epidemiology of frontotemporal dementia" [PMID 23611343]:

• Chromosome 9 open reading frame 72 (C9orf72), chromosomal location 9p21.2, found by association studies of familial FTD-MND, followed by mutation analysis of positional candidate genes. Some sporadic cases of FTD-MND have this mutation. Psychosis at presentation is not uncommon in carriers.
• Progranulin (GRN), location 17q21.32, by linkage analysis followed by mutation analysis of positional candidate genes.
• Microtubule-associated protein tau (MAPT), location 17q21.32, identified by linkage analysis of familial FTD with parkinsonism and gene-phenotype correlation.
• Valosin-containing protein (VCP), location 9p13.3, by linkage analysis of a familial disorder characterized by inclusion body myopathy with osteolytic bone disease and FTD.
• Chromatin-modifying protein 2B (CHMP2B), location 3p11.2, by linkage analysis.

[PMID 22890575] The genetics and neuropathology of frontotemporal lobar degeneration.

[PMID 22732773] Advances in understanding the molecular basis of frontotemporal dementia.

[PMID 22536193] Genetics of Frontotemporal Lobar Degeneration.