Have data from 23andMe or Ancestry? Make a report automatically with Promethease !


From SNPedia

HLA-DO is dimeric protein that is part of down-regulating HLA-DM, coded by HLA-DOA and HLA-DOB. DOB has minimal variation.

HLA-DOA (rs9276977) was significantly associated with RA in African-Americans. rs419434, upstream DOA, was correlated with T1D risk.