IL4
From SNPedia
is a | gene |
is | mentioned by |
Full name | interleukin 4 |
EntrezGene | 3565 |
PheGenI | 3565 |
VariationViewer | 3565 |
ClinVar | IL4 |
GeneCards | IL4 |
dbSNP | 3565 |
Diseases | IL4 |
SADR | 3565 |
HugeNav | 3565 |
wikipedia | IL4 |
IL4 | |
gopubmed | IL4 |
EVS | IL4 |
HEFalMp | IL4 |
MyGene2 | IL4 |
23andMe | IL4 |
UniProt | P05112 |
Ensembl | ENSG00000113520 |
OMIM | 147780 |
# SNPs | 11 |
Max Magnitude | Chromosome position | Summary | |
---|---|---|---|
rs2070874 | 0 | 132,674,018 | |
rs2227284 | 0 | 132,677,033 | |
rs2243248 | 0 | 132,672,952 | |
rs2243250 | 2 | 132,673,462 | |
rs2243266 | 0 | 132,678,097 | |
rs2243267 | 0 | 132,678,194 | |
rs2243268 | 0 | 132,678,271 | |
rs2243270 | 0 | 132,678,417 | |
rs2243274 | 0 | 132,679,140 | |
rs2243289 | 0 | 132,682,440 | |
rs2243290 | 0 | 132,682,477 |
The IL4 gene encodes interleukin 4, a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL4, Th2 cells subsequently produce additional IL4 in a positive feedback loop. It is closely related and has functions similar to IL13 (Interleukin 13).