IRS1
From SNPedia
is a | gene |
is | mentioned by |
EntrezGene | 3667 |
PheGenI | 3667 |
VariationViewer | 3667 |
ClinVar | IRS1 |
GeneCards | IRS1 |
dbSNP | 3667 |
Diseases | IRS1 |
SADR | 3667 |
HugeNav | 3667 |
wikipedia | IRS1 |
IRS1 | |
gopubmed | IRS1 |
EVS | IRS1 |
HEFalMp | IRS1 |
MyGene2 | IRS1 |
23andMe | IRS1 |
# SNPs | 3 |
Max Magnitude | Chromosome position | Summary | |
---|---|---|---|
rs104893642 | 0 | 226,796,916 | |
rs1801123 | 0 | 226,796,327 | |
rs1801278 | 0 | 226,795,828 |
[PMID 17914103] The INSR A-603G promoter SNP, which is located within a known Sp1-binding site, was associated with the risk of colorectal cancer, with carriers of the G allele having a decreased risk (odds ratios (OR) 0.71, 95% confidence interval (CI) 0.54-0.93). Carrying the variant allele of the IRS1 Gly972Arg rs1801278 SNP further decreased the risk among the INSR-603G allele carriers (OR 0.28, 95% CI 0.11-0.70)