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Musical abilities

From SNPedia


Musical abilities are a diverse phenotype that includes both acquired and inherited abilities, including musical aptitude. The doctoral thesis by Jaana Oikkonen, "Genetics and genomics of musical abilities", published October 2016, is aimed at studying the genetic components affecting musical abilities and capacitiesː like abilities to identify pitch, tone duration and sound patterns, which can be considered as basic components of musicality, as well as realisation of music abilities, namely music practice, musicianship, composing, arranging and improvising. The thesis contains a list of the top 40 genes and biomarkers.

Top ranked genes in Convergent functional genomics (CFG) analysis of music-related abilities[edit]

EGR1

FOS

FOXP2

ARC

BDNF

GRIN2B

SYT4

PHIP

MAPK10

DRD1

SNCA

NR4A3

IRS2

ARHGAP24

MTMR2

NR4A2

DUSP1

DUSP5

PKIA

PNISR

TET2

UBE2D3

FAM13A

NUDT9

DOPEY2

NTRK2

AVPR1A

FOSL2

HLA-A

FBXL3

LASP1

RBFOX1

SNX10

ARID1B

POMC

SHFM1

Besides these genes, cortisol, dopamine, estradiol and noradrenalin have been identified to be among the top biomarkers.

Publications[edit]

[PMID 26909693OA-icon.png] Creative Activities in Music--A Genome-Wide Linkage Analysis.

[PMID 26879527OA-icon.png] Detecting signatures of positive selection associated with musical aptitude in the human genome.

[PMID 25154354] Genomics approaches to study musical aptitude.

[PMID 24614497OA-icon.png] A genome-wide linkage and association study of musical aptitude identifies loci containing genes related to inner ear development and neurocognitive functions.

[PMID 23591402OA-icon.png] The genome-wide landscape of copy number variations in the MUSGEN study provides evidence for a founder effect in the isolated Finnish population.

[PMID 23460800OA-icon.png] Genome-wide copy number variation analysis in extended families and unrelated individuals characterized for musical aptitude and creativity in music.

[PMID 21307861] Association of the arginine vasopressin receptor 1A (AVPR1A) haplotypes with listening to music.