Talk:I5005437

Given the table on Congenital adrenal hyperplasia and the chart for Rs9378252 I think it's fairly safe to say the risk allele is T. Thinking we should just straight up copy the chart from that SNP over to this one. Thoughts?

agreed. fixed. --- cariaso 15:59, 14 July 2015 (UTC)

With the prevalence of this allele (~13% of OpenSNP users) and the fact that multiple sources list rs9378252 as benign, should the magnitude of this variant be lowered and/or the repute possibly changed? I also have some doubts of the accuracy given that almost no OpenSNP user is homozygous for the risk allele and 23andMe's history of miscalls in this region (i5005436;rs7755898;rs7769409). I am new to this, so apologies in advance if I am mistaken. — Neverknowsbest (talk) 00:48, 16 November 2015 (UTC)

SNPedia is not 23andMepedia. For Rs7755898(C;T) it was possible that someone on a different platform would find it, so the magnitude should remain high. but I5005437 is a 23andMe only ID, so reducing the magnitude seems like a fine solution. --- cariaso 00:54, 16 November 2015 (UTC)

upon further review rs9378252 is benign according to clinvar (exactly as you'd said), so I've dropped the magnitude and repute for both positions. --- cariaso 01:08, 16 November 2015 (UTC)