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DDC

From SNPedia

is agene
is mentioned by
Full namedopa decarboxylase (aromatic L-amino acid decarboxylase)
Other namesAADC
EntrezGene1644
PheGenI1644
VariationViewer1644
ClinVarDDC
dbSNP1644
SADR1644
HugeNav1644
wikipediaDDC
googleDDC
gopubmedDDC
EVSDDC
HEFalMpDDC
MyGene2DDC
23andMeDDC
UniProtP20711
EnsemblENSG00000132437
OMIM107930
# SNPs26
 Max MagnitudeChromosome positionSummary
rs1157546150,479,485
rs11761683150,475,181
rs11974297150,550,562
rs12718541150,482,446
rs137853207050,539,926
rs137853208050,504,025
rs137853209050,495,369
rs137853210050,529,339
rs137853211050,539,958
rs137853212050,499,201
rs145137150,485,353
rs145137550,555,014
rs147075050,508,950
rs201951824050,476,625
rs2044859150,544,864
rs206076250,461,686
rs224204150,461,751
rs2329340150,552,531
rs373527350,529,166
rs375747250,470,285
rs383709150,561,043
rs6264050,544,037
rs659296150,505,192
rs780923450,542,681
rs92145150,555,587
rs99885050,539,690

catalyzes several decarboxylation reactions:

  • L-DOPA to dopamine - a neurotransmitter
  • 5-HTP to serotonin - also a neurotransmitter
  • tryptophan to tryptamine


per OMIM, Ma et al. (2005) [PMID 15879433] found two different DDC haplotypes associated with nicotine dependence in African Americans and European Americans (with measures of smoking quantity [SQ], heaviness of smoking index [HSI], and the Fagerstrom test for ND [FTND])