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From SNPedia

Magnitude 3
Repute Good
Summary Lowest risk (13% of white women) of Atrial Fibrillation reported by 23andMe
Criteria Gs273/criteria

The two atrial fibrillation SNPs mentioned by 23andMe are both normal. This causes the heart to form normally and gives the lowest risk of Atrial Fibrillation (quivering of the top part of the heart) that 23andMe reports. It also seems to lower the risk of Cardioembolic ischemic stroke (blocked blood flow to the brain) although 23andMe doesn't mention that. For European women, 23andMe reports this as a 13.0% risk, compared to the 15.9% average. The risk is higher for men. Based on many quality studies, and confirmed for Europeans and partly for Asians.