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rs1001179

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0.6x decreased acoustic neuroma risk
(A;G) 0.6x decreased acoustic neuroma risk
(G;G) normal
ReferenceGRCh38 38.1/141
Chromosome11
Position34438684
GeneCAT
is asnp
is mentioned by
dbSNPrs1001179
ebirs1001179
HLIrs1001179
Exacrs1001179
Varsomers1001179
Maprs1001179
PheGenIrs1001179
hapmaprs1001179
1000 genomesrs1001179
hgdprs1001179
ensemblrs1001179
gopubmedrs1001179
geneviewrs1001179
scholarrs1001179
googlers1001179
pharmgkbrs1001179
gwascentralrs1001179
openSNPrs1001179
23andMers1001179
23andMe allrs1001179
SNP Nexus

SNPshotrs1001179
SNPdbers1001179
MSV3drs1001179
GWAS Ctlgrs1001179
GMAF0.123
Max Magnitude
? (A;A) (A;G) (G;G) 28

A study of non-Hispanic Caucasians with various types of brain tumors concluded that there was an decreased risk of acoustic neuroma (odds ratio 0.6, CI: 0.3-1.0) associated with the rs1001179(A) allele, as oriented in dbSNP orientation (and not as published).[PMID 18682580OA-icon.png]


[PMID 19863340] Influence of the polymorphism in candidate genes on late cardiac damage in patients treated due to acute leukemia in childhood


[PMID 20110814OA-icon.png] Air pollution and homocysteine: more evidence that oxidative stress-related genes modify effects of particulate air pollution



[PMID 21795425OA-icon.png] Genetic Variation in Myeloperoxidase Modifies the Association of Serum {alpha}-Tocopherol with Aggressive Prostate Cancer among Current Smokers


[PMID 21338322] Parameters of oxidative stress, DNA damage and DNA repair in type 1 and type 2 diabetes mellitus


[PMID 22712453] Effects of rs769217 and rs1001179 polymorphisms of catalase gene on blood catalase, carbohydrate and lipid biomarkers in diabetes mellitus


[PMID 16385446OA-icon.png] A testing framework for identifying susceptibility genes in the presence of epistasis.


[PMID 16453382] No evidence for a major effect of two common polymorphisms of the catalase gene in type 1 diabetes susceptibility.


[PMID 16820586OA-icon.png] Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery.


[PMID 18248894] Short arm of chromosome 11 and sporadic Alzheimer's disease: catalase and cathepsin D gene polymorphisms.


[PMID 18483329] Effect modification by catalase genotype suggests a role for oxidative stress in the association of hormone replacement therapy with postmenopausal breast cancer risk.


[PMID 18606005OA-icon.png] Detection of catalase as a major protein target of the lipid peroxidation product 4-HNE and the lack of its genetic association as a risk factor in SLE.


[PMID 18988661OA-icon.png] Glutathione-S-transferase (GST) P1, GSTM1, exercise, ozone and asthma incidence in school children.


[PMID 19505917OA-icon.png] Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.


[PMID 20049130OA-icon.png] Black carbon exposure, oxidative stress genes, and blood pressure in a repeated-measures study.


[PMID 20445800OA-icon.png] Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy.


GET Evidence
rs1001179
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.12931
summary



[PMID 23961996OA-icon.png] A catalase promoter variant rs1001179 is associated with visual acuity but not with primary angle closure glaucoma in Saudi patients


[PMID 23363810] Prostate disease risk factors among a New Zealand cohort


[PMID 24215654] Analysis of Catalase SNP rs1001179 in Saudi patients with Primary Open Angle Glaucoma


[PMID 23053794OA-icon.png] Polymorphisms in oxidative stress genes, physical activity, and breast cancer risk.


[PMID 23325794] Genetic polymorphisms in catalase and CYP1B1 determine DNA adduct formation by benzo(a)pyrene ex vivo.


[PMID 25248722] Genetic Polymorphism of CAT C-262 T and Susceptibility to Breast Cancer, a Case-Control Study and Meta-Analysis of the Literatures


[PMID 25573779] Host genetic variations in glutathione-S-transferases, superoxide dismutases and catalase genes influence susceptibility to malaria infection in an Indian population


[PMID 24517502] Gene variants encoding proteins involved in antioxidant defense system and the clinical expression of Wilson disease