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rs1012729

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) normal
(A;G) altered pediatric blood pressure
(G;G) altered pediatric blood pressure
ReferenceGRCh38 38.1/141
Chromosome12
Position878316
GeneWNK1
is asnp
is mentioned by
dbSNPrs1012729
ebirs1012729
HLIrs1012729
Exacrs1012729
Varsomers1012729
Maprs1012729
PheGenIrs1012729
hapmaprs1012729
1000 genomesrs1012729
hgdprs1012729
ensemblrs1012729
gopubmedrs1012729
geneviewrs1012729
scholarrs1012729
googlers1012729
pharmgkbrs1012729
gwascentralrs1012729
openSNPrs1012729
23andMers1012729
23andMe allrs1012729
SNP Nexus

SNPshotrs1012729
SNPdbers1012729
MSV3drs1012729
GWAS Ctlgrs1012729
GMAF0.2865
Max Magnitude
? (A;A) (A;G) (G;G) 28
rs1012729 is a SNP in the WNK lysine deficient protein kinase 1 WNK1 gene.

In the Avon Longitudinal Study of Parent and Children Study (5326 subjects measured for systolic blood pressure at 11 years of age), rs1012729(G) carriers were associated with a gender-adjusted change in a diastolic blood pressure gradient of -0.11 mm Hg/y (CI: -0.20 to -0.03 mm Hg/y; p=0.0054). This variant also showed association with systolic blood pressure. [PMID 18809789]