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rs10486567

From SNPedia

Orientationplus
Stabilizedplus
Make rs10486567(A;A)
Make rs10486567(A;G)
Make rs10486567(G;G)
ReferenceGRCh38 38.1/141
Chromosome7
Position27936944
GeneJAZF1
is asnp
is mentioned by
dbSNPrs10486567
ebirs10486567
HLIrs10486567
Exacrs10486567
Varsomers10486567
Maprs10486567
PheGenIrs10486567
hapmaprs10486567
1000 genomesrs10486567
hgdprs10486567
ensemblrs10486567
gopubmedrs10486567
geneviewrs10486567
scholarrs10486567
googlers10486567
pharmgkbrs10486567
gwascentralrs10486567
openSNPrs10486567
23andMers10486567
23andMe allrs10486567
SNP Nexus

SNPshotrs10486567
SNPdbers10486567
MSV3drs10486567
GWAS Ctlgrs10486567
GMAF0.4541
Max Magnitude
? (A;A) (A;G) (G;G) 28
nature identifies rs10486567 rs10993994 rs10896449 in prostate cancer
GWAS
SNP rs10486567
PubMedID [PMID 18264096]
Condition Prostate cancer (aggressive)
Gene JAZF1
Risk Allele G
pValue 2.00E-006
OR 1.12
95% CI 1.02-1.25


OMIM606246
DescJUXTAPOSED WITH ANOTHER ZINC FINGER GENE 1; JAZF1
Variant
Relatedalso
[PMID 20406958OA-icon.png] Refining the Prostate Cancer Genetic Association within the JAZF1 Gene on Chromosome 7p15.2

[PMID 20460480OA-icon.png] Susceptibility loci associated with prostate cancer progression and mortality


[PMID 18794092OA-icon.png] Association of prostate cancer risk variants with clinicopathologic characteristics of the disease.


[PMID 18974127OA-icon.png] Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer.


[PMID 19104501OA-icon.png] Prostate cancer genomics: towards a new understanding.


[PMID 19318432OA-icon.png] Generalizability of associations from prostate cancer genome-wide association studies in multiple populations.


[PMID 19366831OA-icon.png] Analysis of recently identified prostate cancer susceptibility loci in a population-based study: associations with family history and clinical features.


[PMID 19434657OA-icon.png] Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients.


[PMID 19549807OA-icon.png] Prostate cancer risk associated loci in African Americans.


[PMID 19838195OA-icon.png] A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.


[PMID 19998368OA-icon.png] HNF1B and JAZF1 genes, diabetes, and prostate cancer risk.


[PMID 20039378OA-icon.png] Estimation of genotype relative risks from pedigree data by retrospective likelihoods.


[PMID 20450899] Individual and cumulative association of prostate cancer susceptibility variants with clinicopathologic characteristics of the disease.


[PMID 20569440OA-icon.png] Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer.


[PMID 20690139] Meta-analysis of genome-wide and replication association studies on prostate cancer.


[PMID 21071540OA-icon.png] Validation of genome-wide prostate cancer associations in men of African descent.


[PMID 21390317OA-icon.png] Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.


[PMID 21538423OA-icon.png] Early onset prostate cancer has a significant genetic component.


GET Evidence
rs10486567
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.328125
summary



[PMID 24411283OA-icon.png] Prostate Cancer (PCa) Risk Variants and Risk of Fatal PCa in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium


[PMID 24497837OA-icon.png] Comprehensive functional annotation of 77 prostate cancer risk Loci


[PMID 24801046OA-icon.png] Gene-environment interactions between JAZF1 and occupational and household lead exposure in prostate cancer among African American men