Have questions? Visit https://www.reddit.com/r/SNPedia

rs10524523

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(-;-) 1.5 lower risk of late-onset Alzheimer's disease
(TTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTT) 3 higher risk for late-onset Alzheimer's disease
Make rs10524523(-;TTTTTTTTTTTTTTTTTTT)
ReferenceGRCh38 38.1/142
Chromosome19
Position44899792
GeneTOMM40
is asnp
is mentioned by
dbSNPrs10524523
ebirs10524523
HLIrs10524523
Exacrs10524523
Varsomers10524523
Maprs10524523
PheGenIrs10524523
hapmaprs10524523
1000 genomesrs10524523
hgdprs10524523
ensemblrs10524523
gopubmedrs10524523
geneviewrs10524523
scholarrs10524523
googlers10524523
pharmgkbrs10524523
gwascentralrs10524523
openSNPrs10524523
23andMers10524523
23andMe allrs10524523
SNP Nexus

SNPshotrs10524523
SNPdbers10524523
MSV3drs10524523
GWAS Ctlgrs10524523
StatusDeleted
Max Magnitude3
Alzheimer's disease

[PMID 20029386OA-icon.png] A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease


[PMID 21263443] APOE E4 status predicts age-related cognitive decline in the ninth decade: longitudinal follow-up of the Lothian Birth Cohort 1921

[PMID 21825236OA-icon.png] Association and Expression Analyses With Single-Nucleotide Polymorphisms in TOMM40 in Alzheimer Disease

[PMID 22008263] TOMM40 rs10524523 Polymorphism's Role in Late-Onset Alzheimer's Disease and in Longevity

[PMID 22359560OA-icon.png] Characterization of the Poly-T Variant in the TOMM40 Gene in Diverse Populations

[PMID 22596268] Biochemical Studies of Poly-T Variants in the Alzheimer's Disease Associated TOMM40 Gene [PMID 20457951OA-icon.png] An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease.

[PMID 24103330] Polymorphism in the TOMM40 gene modifies the risk of developing sporadic inclusion body myositis and the age of onset of symptoms [PMID 22863908OA-icon.png] A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging.


[PMID 23792692] Role of TOMM40 rs10524523 polymorphism in onset of alzheimer's disease caused by the PSEN1 M146L mutation.

[PMID 25862420] The effect of TOMM40 on spatial navigation in amnestic mild cognitive impairment