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rs11572103

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0 common in complete genomics
Make rs11572103(A;T)
Make rs11572103(T;T)
ReferenceGRCh38 38.1/142
Chromosome10
Position95058349
GeneCYP2C8
is asnp
is mentioned by
dbSNPrs11572103
ebirs11572103
HLIrs11572103
Exacrs11572103
Varsomers11572103
Maprs11572103
PheGenIrs11572103
hapmaprs11572103
1000 genomesrs11572103
hgdprs11572103
ensemblrs11572103
gopubmedrs11572103
geneviewrs11572103
scholarrs11572103
googlers11572103
pharmgkbrs11572103
gwascentralrs11572103
openSNPrs11572103
23andMers11572103
23andMe allrs11572103
SNP Nexus

SNPshotrs11572103
SNPdbers11572103
MSV3drs11572103
GWAS Ctlgrs11572103
GMAF0.03903
Max Magnitude0
? (A;A) (A;T) (T;T) 28
[PMID 22531455OA-icon.png] Distribution of human CYP2C8*2 allele in three different African populations


[PMID 19761371OA-icon.png] Cytochrome P450 2C8 pharmacogenetics: a review of clinical studies.


[PMID 20389299OA-icon.png] Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism.


GET Evidence
CYP2C8-I269F
aa_change Ile269Phe
aa_change_short I269F
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.0561443
summary 2x lower clearance for paclitaxel.



[PMID 23133420OA-icon.png] Pharmacogenomic Diversity among Brazilians: Influence of Ancestry, Self-Reported Color, and Geographical Origin.