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rs1160312

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2 1.6x increased risk of Male Pattern Baldness.
(A;G) 2 1.6x increased risk of Male Pattern Baldness.
(G;G) 2 Reduced risk of Baldness.
ReferenceGRCh38 38.1/141
Chromosome20
Position22069865
GeneC19orf26
is asnp
is mentioned by
dbSNPrs1160312
ebirs1160312
HLIrs1160312
Exacrs1160312
Varsomers1160312
Maprs1160312
PheGenIrs1160312
hapmaprs1160312
1000 genomesrs1160312
hgdprs1160312
ensemblrs1160312
gopubmedrs1160312
geneviewrs1160312
scholarrs1160312
googlers1160312
pharmgkbrs1160312
gwascentralrs1160312
openSNPrs1160312
23andMers1160312
23andMe allrs1160312
SNP Nexus

SNPshotrs1160312
SNPdbers1160312
MSV3drs1160312
GWAS Ctlgrs1160312
GMAF0.3926
Max Magnitude2
? (A;A) (A;G) (G;G) 28
nature Baldness OR = 1.60, P = 1.1 times 10-14). see also gs122

The risk allele is assumed to be rs1160312(A). Note that a haplotype consisting of rs201571(T) - rs6036025(G) has a perfect correlation (r2 = 1) with rs1160312(A), at least in the Caucasian population studied.

GWAS snp
PMID [PMID 18849991OA-icon.png]
Trait Male-pattern baldness
Title Male-pattern baldness susceptibility locus at 20p11
Risk Allele A
P-val 1E-14
Odds Ratio 1.60 [1.42-1.80] (males)
OMIM612421
DescALOPECIA, ANDROGENETIC, 3; AGA3
Variant
Relatedalso




GET Evidence
rs1160312
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.5625
summary



[PMID 24386074OA-icon.png] Androgenic Alopecia Is Associated with Less Dietary Soy, Higher Blood Vanadium and rs1160312 1 Polymorphism in Taiwanese Communities