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rs11803731

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2 straighter hair
(T;T) 2 curlier hair
Make rs11803731(A;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position152110849
GeneTCHH
is asnp
is mentioned by
dbSNPrs11803731
ebirs11803731
HLIrs11803731
Exacrs11803731
Varsomers11803731
Maprs11803731
PheGenIrs11803731
hapmaprs11803731
1000 genomesrs11803731
hgdprs11803731
ensemblrs11803731
gopubmedrs11803731
geneviewrs11803731
scholarrs11803731
googlers11803731
pharmgkbrs11803731
gwascentralrs11803731
openSNPrs11803731
23andMers11803731
23andMe allrs11803731
SNP Nexus

SNPshotrs11803731
SNPdbers11803731
MSV3drs11803731
GWAS Ctlgrs11803731
GMAF0.1006
Max Magnitude2
? (A;A) (A;T) (T;T) 28
rs11803731, a SNP in the Trichohyalin gene (TCHH) gene, is estimated to account for 6% of the variance in hair morphology (ie hair curliness) based on a study of Australians of European ancestry.[PMID 19896111OA-icon.png]

10.1038/ncomms10815 A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features

GWAS snp
PMID [PMID 19896111OA-icon.png]
Trait Hair morphology
Title Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans
Risk Allele A
P-val 3E-31
Odds Ratio 6.11 [NR] % variance
OMIM139450
Desc
Variant
Relatedalso
[PMID 20585627OA-icon.png] Web-based, participant-driven studies yield novel genetic associations for common traits.


GET Evidence
TCHH-L790M
aa_change Leu790Met
aa_change_short L790M
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.132544
summary



[PMID 26414620] Evaluation of the predictive capacity of DNA variants associated with straight hair in Europeans