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rs12272004

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0
Make rs12272004(A;A)
Make rs12272004(A;C)
ReferenceGRCh38 38.1/141
Chromosome11
Position116733008
is asnp
is mentioned by
dbSNPrs12272004
ebirs12272004
HLIrs12272004
Exacrs12272004
Varsomers12272004
Maprs12272004
PheGenIrs12272004
hapmaprs12272004
1000 genomesrs12272004
hgdprs12272004
ensemblrs12272004
gopubmedrs12272004
geneviewrs12272004
scholarrs12272004
googlers12272004
pharmgkbrs12272004
gwascentralrs12272004
openSNPrs12272004
23andMers12272004
23andMe allrs12272004
SNP Nexus

SNPshotrs12272004
SNPdbers12272004
MSV3drs12272004
GWAS Ctlgrs12272004
GMAF0.07576
Max Magnitude0
? (A;A) (A;C) (C;C) 28
[PMID 19185284OA-icon.png] rs12272004 associated with alpha-tocopherol (meta-analysis p = 7.8 x 10(-10)) levels; the association was substantially weaker when adjusted for triglyceride levels (p = 0.002).
GWAS snp
PMID [PMID 19060911OA-icon.png]
Trait Cholesterol, total
Title Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
Risk Allele C
P-val 7E-7
Odds Ratio 0.11 [NR] SD decrease






[PMID 19474294OA-icon.png] Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.


[PMID 20502693OA-icon.png] Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.


GET Evidence
rs12272004
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.0703125
summary



[PMID 23452379] APOA5 genotype influences the association between 25-hydroxyvitamin D and high density lipoprotein cholesterol.