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rs12304921

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 normal
(A;G) 2.5x risk type 2 diabetes
(G;G) 1.9x risk type 2 diabetes
ReferenceGRCh38 38.1/141
Chromosome12
Position50963759
GeneHIGD1C
is asnp
is mentioned by
dbSNPrs12304921
ebirs12304921
HLIrs12304921
Exacrs12304921
Varsomers12304921
Maprs12304921
PheGenIrs12304921
hapmaprs12304921
1000 genomesrs12304921
hgdprs12304921
ensemblrs12304921
gopubmedrs12304921
geneviewrs12304921
scholarrs12304921
googlers12304921
pharmgkbrs12304921
gwascentralrs12304921
openSNPrs12304921
23andMers12304921
23andMe allrs12304921
SNP Nexus

SNPshotrs12304921
SNPdbers12304921
MSV3drs12304921
GWAS Ctlgrs12304921
GMAF0.2369
Max Magnitude0
? (A;A) (A;G) (G;G) 28
rs12304921 has been reported in a large study to be associated with type-2 diabetes.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 2.50 (CI 1.53-4.09), and for homozygotes, 1.94 (CI 1.20-3.15). [PMID 17554300OA-icon.png]

GWAS
SNP rs12304921
PubMedID [PMID 17554300OA-icon.png]
Condition Type 2 diabetes
Gene NR
Risk Allele G
pValue 7.00E-006
OR 2.5
95% CI 1.53-4.09



GET Evidence
rs12304921
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.203125
summary