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rs12520016

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) G allele associated with intermediate eye color and decreased risk of melanoma
(G;T) G allele associated with intermediate eye color and decreased risk of melanoma
(T;T) 0 most common/normal
ReferenceGRCh38 38.1/141
Chromosome5
Position6767199
GeneLOC102724943
is asnp
is mentioned by
dbSNPrs12520016
dbSNP (classic)rs12520016
ClinGenrs12520016
ebirs12520016
HLIrs12520016
Exacrs12520016
Gnomadrs12520016
Varsomers12520016
LitVarrs12520016
Maprs12520016
PheGenIrs12520016
Biobankrs12520016
1000 genomesrs12520016
hgdprs12520016
ensemblrs12520016
geneviewrs12520016
scholarrs12520016
googlers12520016
pharmgkbrs12520016
gwascentralrs12520016
openSNPrs12520016
23andMers12520016
SNPshotrs12520016
SNPdbers12520016
MSV3drs12520016
GWAS Ctlgrs12520016
GMAF0.04408
Max Magnitude0
? (G;G) (G;T) (T;T) 28


GWAS snp
PMID [PMID 23548203OA-icon.png]
Trait Eye color
Title Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
Risk Allele G
P-val 9E-7
Odds Ratio .42 [0.26-0.58] unit increase


The 'G' allele is associated with a more "intermediate" (Green) eye color and lower risk of melanoma, compared to the 'T' allele. [PMID 23548203OA-icon.png]