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rs13376333

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0
(C;T) 1.5 1.5x higher risk of atrial fibrillation
(T;T) 2 ~2x higher risk of atrial fibrillation
ReferenceGRCh38 38.1/141
Chromosome1
Position154841877
GeneKCNN3
is asnp
is mentioned by
dbSNPrs13376333
ebirs13376333
HLIrs13376333
Exacrs13376333
Varsomers13376333
Maprs13376333
PheGenIrs13376333
hapmaprs13376333
1000 genomesrs13376333
hgdprs13376333
ensemblrs13376333
gopubmedrs13376333
geneviewrs13376333
scholarrs13376333
googlers13376333
pharmgkbrs13376333
gwascentralrs13376333
openSNPrs13376333
23andMers13376333
23andMe allrs13376333
SNP Nexus

SNPshotrs13376333
SNPdbers13376333
MSV3drs13376333
GWAS Ctlgrs13376333
GMAF0.2199
Max Magnitude2
? (C;C) (C;T) (T;T) 28

news atrial fibrillation rs13376333 in KCNN3, with an odds ratio (OR) of 1.5 per copy of rs13376333(T); CI: 1.40–1.64, p = 1.83 × 10e-21.

spitoon

GWAS snp
PMID [PMID 20173747OA-icon.png]
Trait Atrial fibrillation
Title Common variants in KCNN3 are associated with lone atrial fibrillation
Risk Allele T
P-val 2E-21
Odds Ratio 1.52 [1.40-1.64]


[PMID 21107608] Significant association of SNP rs2106261 in the ZFHX3 gene with atrial fibrillation in a Chinese Han GeneID population

OMIM608583
Desc
Variant
Relatedalso
[PMID 21760908OA-icon.png] Association between variants on chromosome 4q25, 16q22 and 1q21 and atrial fibrillation in the Polish population


[PMID 22019810] Significant Association of rs13376333 in KCNN3 on Chromosome 1q21 With Atrial Fibrillation in a Taiwanese Population


GET Evidence
rs13376333
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.1875
summary



[PMID 23428961OA-icon.png] Common genetic polymorphism at 4q25 locus predicts atrial fibrillation recurrence after successful cardioversion.


[PMID 24978901] Association between SNP rs13376333 and rs1131820 in the KCNN3 gene and atrial fibrillation in the Chinese Han population


[PMID 25684755] Common Genetic Variants and Response to Atrial Fibrillation Ablation


[PMID 26370375] KCNN3 SNP rs13376333 on Chromosome 1q21 Confers Increased Risk of Atrial Fibrillation