Have questions? Visit https://www.reddit.com/r/SNPedia

rs1495377

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 0 normal
(C;G) 1.3x risk type-2 diabetes
(G;G) 1.5x risk type-2 diabetes
ReferenceGRCh38 38.1/141
Chromosome12
Position71183321
is asnp
is mentioned by
dbSNPrs1495377
ebirs1495377
HLIrs1495377
Exacrs1495377
Varsomers1495377
Maprs1495377
PheGenIrs1495377
hapmaprs1495377
1000 genomesrs1495377
hgdprs1495377
ensemblrs1495377
gopubmedrs1495377
geneviewrs1495377
scholarrs1495377
googlers1495377
pharmgkbrs1495377
gwascentralrs1495377
openSNPrs1495377
23andMers1495377
23andMe allrs1495377
SNP Nexus

SNPshotrs1495377
SNPdbers1495377
MSV3drs1495377
GWAS Ctlgrs1495377
GMAF0.3462
Max Magnitude0
? (C;C) (C;G) (G;G) 28
rs1495377 has been reported in a large study to be associated with type-2 diabetes.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.28 (CI 1.11-1.49), and for homozygotes, 1.51 (CI 1.28-1.78). [PMID 17554300OA-icon.png]

Note: orientation of this SNP is presumed correct but should be confirmed

GWAS
SNP rs1495377
PubMedID [PMID 17554300OA-icon.png]
Condition Type 2 diabetes
Gene NR
Risk Allele G
pValue 7.00E-006
OR 1.28
95% CI 1.11-1.49



GWAS snp
PMID [PMID 22137330]
Trait
Title Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk.
Risk Allele
P-val 0.000002
Odds Ratio None None


GET Evidence
rs1495377
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.671875
summary