|(A;A)||1.5||>1.36x risk for prostate cancer|
|(A;C)||1.36x risk for prostate cancer|
Although the association was found in a study of Caucasian patients, it was also reported to be statistically significant in a population of 210 African-Americans with prostate cancer. [PMID 18073375]
According to , "The odds ratio for aggressive prostate cancer ranged from 1.29 to 1.50 in men with one or two copies of the mutant A allele compared with noncarriers."
rs1571801 is located in the DAB2IP gene and encodes a novel Ras GTPase-activating protein and putative prostate tumor suppressor.
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[PMID 23159463] Genetic sequence variants are associated with severity of lower urinary tract symptoms and prostate cancer susceptibility.