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rs1585215

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0 normal
(A;G) 2 2x increased risk for Hodgkin lymphoma
(G;G) 2.1 3.5x increased risk for Hodgkin lymphoma
ReferenceGRCh38 38.1/141
Chromosome4
Position102523317
GeneNFKB1
is asnp
is mentioned by
dbSNPrs1585215
ebirs1585215
HLIrs1585215
Exacrs1585215
Varsomers1585215
Maprs1585215
PheGenIrs1585215
hapmaprs1585215
1000 genomesrs1585215
hgdprs1585215
ensemblrs1585215
gopubmedrs1585215
geneviewrs1585215
scholarrs1585215
googlers1585215
pharmgkbrs1585215
gwascentralrs1585215
openSNPrs1585215
23andMers1585215
23andMe allrs1585215
SNP Nexus

SNPshotrs1585215
SNPdbers1585215
MSV3drs1585215
GWAS Ctlgrs1585215
GMAF0.292
Max Magnitude2.1
? (A;A) (A;G) (G;G) 28
rs1585215 is a SNP in the NFKB1 gene.

A population-based case-control study including 473 cases of Hodgkin lymphoma concluded that increased risk for the disease was significantly associated with rs1585215. The odds ratio for rs1585215(G;G) homozygotes was 3.5 (CI: 2.2-5.7, Ptrend = 1.7 x 10(-8)), and for (A;G) heterozygotes, 2.1 (CI: 1.5-2.9).[PMID 19223558OA-icon.png]


[PMID 25422198] Polymorphic variation of inflammation-related genes and risk of non-Hodgkin lymphoma for Uygur and Han Chinese in Xinjiang