Rs16942

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is asnp
is mentioned by
dbSNPrs16942
hapmaprs16942
hgdprs16942
ensemblrs16942
gopubmedrs16942
scholarrs16942
googlers16942
pharmgkbrs16942
hgvbaseg2prs16942
medrefsnprs16942
23andMers16942
SNP Nexus

GeneBRCA1
Chromosome17
Orientationminus
Position38497525
GenotypeEffect
rs16942(A;A)
rs16942(A;G)*?
rs16942(G;G)


Genotypes Magnitude Summary
Rs16942(A;A) 00
Rs16942(G;G) 22

This SNP, a variant in the BRCA1 gene, is 1 of 25 SNPs reported to represent independently minor, but cumulatively significant, increased risk for breast cancer. [PMID 17341484]

For this particular SNP, the risk (minor) allele is (G).

For details of all 25 SNPs in this group, along with the two methods used to calculate overall risk estimates for breast cancer, refer to the SNPedia breast cancer entry or BRCA1 and BRCA2.

Neighborrs2227945
Distance130
? (A;A) (A;G) (G;G)


Venter snp
Source plos
Gene BRCA1
allele C
frequency 0.356
sift TOLERATED
HuRef 1103645327477
Disease Association Defects in BRCA1 are a cause of genetic susceptibility to ovarian cancer (MIM:113705).