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rs1801177

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common in clinvar
Make rs1801177(A;A)
Make rs1801177(A;G)
ReferenceGRCh38 38.1/141
Chromosome8
Position19948197
GeneLPL
is asnp
is mentioned by
dbSNPrs1801177
ebirs1801177
HLIrs1801177
Exacrs1801177
Varsomers1801177
Maprs1801177
PheGenIrs1801177
hapmaprs1801177
1000 genomesrs1801177
hgdprs1801177
ensemblrs1801177
gopubmedrs1801177
geneviewrs1801177
scholarrs1801177
googlers1801177
pharmgkbrs1801177
gwascentralrs1801177
openSNPrs1801177
23andMers1801177
23andMe allrs1801177
SNP Nexus

SNPshotrs1801177
SNPdbers1801177
MSV3drs1801177
GWAS Ctlgrs1801177
GMAF0.01423
Max Magnitude0

[PMID 20429872OA-icon.png] Additive effects of LPL, APOA5 and APOE variant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study

OMIM609708
Desc
Variant0035
Relatedalso


ClinVar
Risk rs1801177(A,C;A,C)
Alt rs1801177(A,C;A,C)
Reference rs1801177(G;G)
Significance Other
Disease Hyperlipidemia Coronary heart disease
Variation info
Gene LPL
CLNDBN Hyperlipidemia, familial combined Coronary heart disease
Reversed 0
HGVS NC_000008.10:g.19805708G>A
CLNSRC OMIM Allelic Variant
CLNACC RCV000001617.2, RCV000157298.1,



[PMID 17357073OA-icon.png] Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol.


[PMID 18513389OA-icon.png] New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background.


[PMID 18922999] Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis.


[PMID 19041386OA-icon.png] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.


[PMID 19131662OA-icon.png] A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.


[PMID 20406163] Fenofibrate and metabolic syndrome.


[PMID 21146168] LPL polymorphism (D9N) predicts cardiovascular disease risk directly and through interaction with CETP polymorphism (TaqIB) in women with high HDL cholesterol and CRP.


[PMID 22236405OA-icon.png] LPL gene variants affect apoC-III response to combination therapy of statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia.


GET Evidence
LPL-D36N
aa_change Asp36Asn
aa_change_short D36N
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.0281651
summary