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rs1937

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common on affy axiom data
Make rs1937(C;C)
Make rs1937(C;G)
ReferenceGRCh38 38.1/142
Chromosome10
Position58385582
GeneTFAM
is asnp
is mentioned by
dbSNPrs1937
ebirs1937
HLIrs1937
Exacrs1937
Varsomers1937
Maprs1937
PheGenIrs1937
hapmaprs1937
1000 genomesrs1937
hgdprs1937
ensemblrs1937
gopubmedrs1937
geneviewrs1937
scholarrs1937
googlers1937
pharmgkbrs1937
gwascentralrs1937
openSNPrs1937
23andMers1937
23andMe allrs1937
SNP Nexus

SNPshotrs1937
SNPdbers1937
MSV3drs1937
GWAS Ctlgrs1937
GMAF0.09412
Max Magnitude0
? (C;C) (C;G) (G;G) 28

[PMID 20977898] Mitochondrial transcription factor A (TFAM) polymorphisms and risk of late-onset Alzheimer's disease in Han Chinese

The C allele of rs1937 appears to be protective against late-onset Alzheimer's disease in Han Chinese. [PMID 20977898]


[PMID 15464268] Possible association of mitochondrial transcription factor A (TFAM) genotype with sporadic Alzheimer disease.


[PMID 16385451OA-icon.png] A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.


[PMID 17497594] Relationship between TFAM gene polymorphisms and endurance capacity in response to training.


[PMID 17537576] Association study of two genetic variants in mitochondrial transcription factor A (TFAM) in Alzheimer's and Parkinson's disease.


[PMID 18430995] Mitochondrial transcription factor A (TFAM) gene variation and risk of late-onset Alzheimer's disease.


[PMID 18451773] A decreased mitochondrial DNA content is related to insulin resistance in adolescents.


GET Evidence
TFAM-S12T
aa_change Ser12Thr
aa_change_short S12T
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.0709635
summary



[PMID 23186209] Mitochondriogenesis genes and extreme longevity.