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rs1992662

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) increased risk for Crohn's disease
(C;T)  ?
(T;T) 0.76x decreased risk for Crohn's disease
ReferenceGRCh38 38.1/141
Chromosome5
Position40393750
GenePTGER4
is asnp
is mentioned by
dbSNPrs1992662
ebirs1992662
HLIrs1992662
Exacrs1992662
Varsomers1992662
Maprs1992662
PheGenIrs1992662
hapmaprs1992662
1000 genomesrs1992662
hgdprs1992662
ensemblrs1992662
gopubmedrs1992662
geneviewrs1992662
scholarrs1992662
googlers1992662
pharmgkbrs1992662
gwascentralrs1992662
openSNPrs1992662
23andMers1992662
23andMe allrs1992662
SNP Nexus

SNPshotrs1992662
SNPdbers1992662
MSV3drs1992662
GWAS Ctlgrs1992662
GMAF0.4013
Max Magnitude
? (C;C) (C;T) (T;T) 28
rs1992662 is a SNP upstream of the PTGER4 gene that was found in a genome-wide association study to be associated with Crohn's disease.

In several European populations, the most common allele, rs1992662(T), was associated with increased risk for Crohn's disease. Conversely, the odds ratio (pooled over several populations) for the minor allele, rs1992662(C), was 0.76 (CI: 0.63-0.91, p=0.0013).[PMID 17684544OA-icon.png]

Neighborrs10512734
Distance247