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rs2071746

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) normal
(A;T) normal
(T;T) may be part of gs124
ReferenceGRCh38 38.1/141
Chromosome22
Position35380679
GeneHMOX1
is asnp
is mentioned by
dbSNPrs2071746
ebirs2071746
HLIrs2071746
Exacrs2071746
Varsomers2071746
Maprs2071746
PheGenIrs2071746
hapmaprs2071746
1000 genomesrs2071746
hgdprs2071746
ensemblrs2071746
gopubmedrs2071746
geneviewrs2071746
scholarrs2071746
googlers2071746
pharmgkbrs2071746
gwascentralrs2071746
openSNPrs2071746
23andMers2071746
23andMe allrs2071746
SNP Nexus

SNPshotrs2071746
SNPdbers2071746
MSV3drs2071746
GWAS Ctlgrs2071746
GMAF0.4995
Max Magnitude
? (A;A) (A;T) (T;T) 28
A case-control study of 300 patients with Alzheimer's disease found that subjects carrying both the rs2071746(T;T) and rs242557(A;A) genotypes had a 6.65x increased risk (CI: 1.12-39.29; p = 0.037) compared to subjects without these risk genotypes.[PMID 18841019]

This combination of SNPs is encapsulated in the gs124 genoset.


[PMID 20039940] Synergistic effect of two oxidative stress-related genes (heme oxygenase-1 and GSK3beta) on the risk of Parkinson's disease


[PMID 20509889OA-icon.png] The polymorphism rs3024505 proximal to IL-10 is associated with risk of ulcerative colitis and Crohns disease in a Danish case-control study

[PMID 20190330] HMOX1 and GST variants modify attenuation of FEF25-75% decline due to PM10 reduction

[PMID 21191307] Heme oxygenase-1 polymorphism is not associated with riskof colorectal cancer: a Danish prospective study


[PMID 21902835OA-icon.png] Effect of Heme Oxygenase-1 Polymorphisms on Lung Function and Gene Expression


[PMID 22666428OA-icon.png] Genetic Analyses of Heme Oxygenase 1 (HMOX1) in Different Forms of Pancreatitis


[PMID 18597895] Gene-gene interaction between heme oxygenase-1 and liver X receptor-beta and Alzheimer's disease risk.


[PMID 18640487OA-icon.png] Association of donor inflammation- and apoptosis-related genotypes and delayed allograft function after kidney transplantation.


[PMID 19406964OA-icon.png] Association of genetic variants with chronic kidney disease in Japanese individuals.


[PMID 19526221OA-icon.png] Heme oxygenase-1 microsatellite polymorphism and haplotypes are associated with the development of acute respiratory distress syndrome.


[PMID 20597111OA-icon.png] Effect of interactions of glutathione S-transferase T1, M1, and P1 and HMOX1 gene promoter polymorphisms with heavy smoking on the risk of rheumatoid arthritis.


[PMID 21270830] Cystic fibrosis modifier genes related to Pseudomonas aeruginosa infection.


[PMID 21275653] Association of heme oxygenase-1 gene polymorphisms with essential hypertension and blood pressure in the Chinese Han population.


[PMID 23042203] Gene polymorphisms in the heme degradation pathway and outcome of severe human sepsis


[PMID 23725037] Polymorphism in the HMOX1 Gene is Associated with High Levels of Fetal Hemoglobin in Brazilian Patients with Sickle Cell Anemia


[PMID 22609818] Genetic polymorphisms of HO-1 and COX-1 are associated with aspirin resistance defined by light transmittance aggregation in Chinese Han patients


[PMID 25016572] Association of heme oxygenase-1 gene rs2071746 polymorphism with vascular outcomes in patients with atherosclerotic stroke


[PMID 26173399] Heme oxygenase-1 promoter polymorphisms and risk of spina bifida


[PMID 26313808OA-icon.png] Heme Oxygenase-1 and 2 Common Genetic Variants and Risk for Restless Legs Syndrome


[PMID 26868429] Heme Oxygenase-1 and 2 Common Genetic Variants and Risk for Multiple Sclerosis.


[PMID 27222475] Genetic polymorphism of the Nrf2 promoter region is associated with vitiligo risk in Han Chinese populations.