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rs2073618

From SNPedia

Orientationminus
Stabilizedminus
Make rs2073618(C;C)
Make rs2073618(C;G)
Make rs2073618(G;G)
ReferenceGRCh38 38.1/141
Chromosome8
Position118951813
GeneCOLEC10, TNFRSF11B
is asnp
is mentioned by
dbSNPrs2073618
ebirs2073618
HLIrs2073618
Exacrs2073618
Varsomers2073618
Maprs2073618
PheGenIrs2073618
hapmaprs2073618
1000 genomesrs2073618
hgdprs2073618
ensemblrs2073618
gopubmedrs2073618
geneviewrs2073618
scholarrs2073618
googlers2073618
pharmgkbrs2073618
gwascentralrs2073618
openSNPrs2073618
23andMers2073618
23andMe allrs2073618
SNP Nexus

SNPshotrs2073618
SNPdbers2073618
MSV3drs2073618
GWAS Ctlgrs2073618
GMAF0.3567
Max Magnitude
? (C;C) (C;G) (G;G) 28

[PMID 20231205] Genetic Variations in Genes Encoding RANK, RANKL, and OPG in Rheumatoid Arthritis: A Case-Control Study


[PMID 22079369] TNFRSF11B gene haplotype and its association with bone mineral density variations in postmenopausal Mexican-Mestizo women


[PMID 21964949OA-icon.png] Influence of polymorphisms in the RANKL/RANK/OPG signaling pathway on volumetric bone mineral density and bone geometry at the forearm in men


[PMID 16583245OA-icon.png] Genetic susceptibility to hip arthroplasty failure--association with the RANK/OPG pathway.


[PMID 19458885OA-icon.png] Association analyses of RANKL/RANK/OPG gene polymorphisms with femoral neck compression strength index variation in Caucasians.


[PMID 20205168] Genetic variation in the RANKL/RANK/OPG signaling pathway is associated with bone turnover and bone mineral density in men.


[PMID 21396799] Genetic polymorphisms and other risk factors associated with bisphosphonate induced osteonecrosis of the jaw.


[PMID 21411255] TNFRSF11B gene polymorphisms 1181G > C and 245T > G as well as haplotype CT influence bone mineral density in postmenopausal women.


GET Evidence
TNFRSF11B-N3K
aa_change Asn3Lys
aa_change_short N3K
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.593125
summary



[PMID 23369128OA-icon.png] Genetic polymorphism of the OPG gene associated with breast cancer


[PMID 24130145] Polymorphism of LRP5, but not of TNFRSF11B, is associated with a decrease in bone mineral density in postmenopausal maya-mestizo women


[PMID 24228244OA-icon.png] SNP rs2073618 of the Osteoprotegerin Gene Is Associated with Diabetic Retinopathy in Slovenian Patients with Type 2 Diabetes


[PMID 24283361] Association Between Seven Common OPG Genetic Polymorphisms and Osteoporosis Risk: A Meta-Analysis


[PMID 23299915] Osteoprotegerin gene rs2073617 and rs3134069 polymorphisms in type 2 diabetes patients and sexspecific rs2073618 polymorphism as a risk factor for diabetic foot.


[PMID 23531404] Association of genetic polymorphisms of RANK, RANKL and OPG with bone mineral density in Chinese peri- and postmenopausal women.


[PMID 25032118OA-icon.png] Exclusion of TNFRSF11B as Candidate Gene for Otosclerosis in Campania Population


[PMID 25323794] TNFRSF11B gene polymorphisms, bone mineral density, and fractures in Slovak postmenopausal women


[PMID 25679449OA-icon.png] A Variant in the Osteoprotegerin Gene Is Associated with Coronary Atherosclerosis in Patients with Rheumatoid Arthritis: Results from a Candidate Gene Study


[PMID 26218592OA-icon.png] RANKL and OPG Polymorphisms Are Associated with Aromatase Inhibitor-Related Musculoskeletal Adverse Events in Chinese Han Breast Cancer Patients


[PMID 26451891] RANK rs1805034 T>C Polymorphism Is Associated with Susceptibility to Gastric Cardia Adenocarcinoma in a Chinese Population


[PMID 26579581] Genetic and environmental predictors of chronic kidney disease in patients with type 2 diabetes and diabetic foot ulcer: a pilot study