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rs2074190

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 2.2x risk for AIA
(C;T) 2.2x risk for AIA
(T;T) 0 common
ReferenceGRCh38 38.1/142
Chromosome17
Position47733844
GeneTBX21
is asnp
is mentioned by
dbSNPrs2074190
ebirs2074190
HLIrs2074190
Exacrs2074190
Varsomers2074190
Maprs2074190
PheGenIrs2074190
hapmaprs2074190
1000 genomesrs2074190
hgdprs2074190
ensemblrs2074190
gopubmedrs2074190
geneviewrs2074190
scholarrs2074190
googlers2074190
pharmgkbrs2074190
gwascentralrs2074190
openSNPrs2074190
23andMers2074190
23andMe allrs2074190
SNP Nexus

SNPshotrs2074190
SNPdbers2074190
MSV3drs2074190
GWAS Ctlgrs2074190
GMAF0.2401
Max Magnitude0
? (C;C) (C;T) (T;T) 28
rs2074190(G;G) and rs2074190(A;G) genotypes for the TBX21 gene are calculated to be at 2.19 fold higher risk (CI: 1.27-3.77) for aspirin-induced asthma (AIA) compared to rs2074190(A;A) homozygotes, based on a study of 72 patients vs 640 controls in a study of a Japanese population. [PMID 15806396]

Note that in this population, but perhaps not others, linkage disequilibrium exists between this SNP located in the first exon, rs2074190, and a SNP located upstream of the gene, rs4794067, with a predictive accuracy of 92%.

Neighborrs2240017
Distance291