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rs2077119

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0.91x decreased risk for T2D
(G;T) 0.91x decreased risk for T2D
(T;T) 0 1x normal risk
ReferenceGRCh38 38.1/141
Chromosome3
Position186612673
GeneAHSG
is asnp
is mentioned by
dbSNPrs2077119
ebirs2077119
HLIrs2077119
Exacrs2077119
Varsomers2077119
Maprs2077119
PheGenIrs2077119
hapmaprs2077119
1000 genomesrs2077119
hgdprs2077119
ensemblrs2077119
gopubmedrs2077119
geneviewrs2077119
scholarrs2077119
googlers2077119
pharmgkbrs2077119
gwascentralrs2077119
openSNPrs2077119
23andMers2077119
23andMe allrs2077119
SNP Nexus

SNPshotrs2077119
SNPdbers2077119
MSV3drs2077119
GWAS Ctlgrs2077119
GMAF0.3792
Max Magnitude0
? (G;G) (G;T) (T;T) 28
rs2077119, also known as -469T/G, is a SNP in the alpha-2-HS-glycoprotein AHSG gene.

In a study of ~3,800 Danish type-2 diabetes patients, pooled with a previous study, the minor rs2077119(G) allele showed a slight protective effect, with an odds ratio of 0.91 (CI: 0.84-0.99, p=0.007).[PMID 18316360]


[PMID 17889958] A promoter polymorphism of the alpha2-HS glycoprotein gene is associated with its transcriptional activity.


[PMID 22024217] Are AHSG polymorphisms directly associated with coronary atherosclerosis?