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rs2107301

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Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 0 normal risk
(C;T)  ?
(T;T) 3 2.5x higher risk for prostate cancer
ReferenceGRCh38 38.1/141
Chromosome12
Position47861787
GeneVDR
is asnp
is mentioned by
dbSNPrs2107301
ebirs2107301
HLIrs2107301
Exacrs2107301
Varsomers2107301
Maprs2107301
PheGenIrs2107301
hapmaprs2107301
1000 genomesrs2107301
hgdprs2107301
ensemblrs2107301
gopubmedrs2107301
geneviewrs2107301
scholarrs2107301
googlers2107301
pharmgkbrs2107301
gwascentralrs2107301
openSNPrs2107301
23andMers2107301
23andMe allrs2107301
SNP Nexus

SNPshotrs2107301
SNPdbers2107301
MSV3drs2107301
GWAS Ctlgrs2107301
GMAF0.3572
Max Magnitude3
? (C;C) (C;T) (T;T) 28
rs2107301 is a SNP in the vitamin D VDR receptor gene.

rs2107301(T;T) homozygotes were associated with an ~2.5x higher risk of prostate cancer compared to homozygote carriers of the more common (C) allele in the 630 Caucasian patients studied.[PMID 17932346]


[PMID 19255064OA-icon.png] Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.


[PMID 19454612OA-icon.png] Vitamin D pathway gene variants and prostate cancer risk.


[PMID 19753122OA-icon.png] Analysis of SNPs and haplotypes in vitamin D pathway genes and renal cancer risk.


[PMID 19956101OA-icon.png] Overview of the Rapid Response data.


[PMID 21948293] Vitamin D Receptor Gene Variants and Esophageal Adenocarcinoma Risk: A Population-Based Case-Control Study.


[PMID 22576141OA-icon.png] No association of vitamin D metabolism-related polymorphisms and melanoma risk as well as melanoma prognosis: a case-control study.


[PMID 24381141] Vitamin D receptor gene polymorphisms and esophageal cancer risk in a Chinese population: a negative study


[PMID 27736940] Vitamin D Receptor Gene Polymorphism and the Risk of Colorectal Cancer: A Nested Case-Control Study.