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rs2145418

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(G;G) 3 9.2x increased thyroid cancer risk
(G;T) 3 5.0x increased thyroid cancer risk
(T;T) 0 normal
ReferenceGRCh38 38.1/141
Chromosome1
Position118422631
is asnp
is mentioned by
dbSNPrs2145418
ebirs2145418
HLIrs2145418
Exacrs2145418
Varsomers2145418
Maprs2145418
PheGenIrs2145418
hapmaprs2145418
1000 genomesrs2145418
hgdprs2145418
ensemblrs2145418
gopubmedrs2145418
geneviewrs2145418
scholarrs2145418
googlers2145418
pharmgkbrs2145418
gwascentralrs2145418
openSNPrs2145418
23andMers2145418
23andMe allrs2145418
SNP Nexus

SNPshotrs2145418
SNPdbers2145418
MSV3drs2145418
GWAS Ctlgrs2145418
GMAF0.2557
Max Magnitude3
? (G;G) (G;T) (T;T) 28
rs2145418 is a SNP in the chromosome 1p12-13 region.

In a case-control association study in a Spanish population, rs2145418 was associated with increased risk for thyroid cancer. rs2145418(G;T) heterozygotes had an odds ratio of 5.0 (CI: 2.85 - 8.83), while (G;G) homozygotes had an increased odds ratio of 9.2 (CI: 4.50 - 21.6), with reported significance of p < 0.0001.[PMID 18559567]