rs2145418
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 2.5 | 9.2x increased thyroid cancer risk |
| (G;T) | 2.2 | 5.0x increased thyroid cancer risk |
| (T;T) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 118422631 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2145418 |
| dbSNP (classic) | rs2145418 |
| ClinGen | rs2145418 |
| ebi | rs2145418 |
| HLI | rs2145418 |
| Exac | rs2145418 |
| Gnomad | rs2145418 |
| Varsome | rs2145418 |
| LitVar | rs2145418 |
| Map | rs2145418 |
| PheGenI | rs2145418 |
| Biobank | rs2145418 |
| 1000 genomes | rs2145418 |
| hgdp | rs2145418 |
| ensembl | rs2145418 |
| geneview | rs2145418 |
| scholar | rs2145418 |
| rs2145418 | |
| pharmgkb | rs2145418 |
| gwascentral | rs2145418 |
| openSNP | rs2145418 |
| 23andMe | rs2145418 |
| SNPshot | rs2145418 |
| SNPdbe | rs2145418 |
| MSV3d | rs2145418 |
| GWAS Ctlg | rs2145418 |
| GMAF | 0.2557 |
| Max Magnitude | 2.5 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs2145418 is a SNP in the chromosome 1p12-13 region.
In a case-control association study in a Spanish population, rs2145418 was associated with increased risk for thyroid cancer. rs2145418(G;T) heterozygotes had an odds ratio of 5.0 (CI: 2.85 - 8.83), while (G;G) homozygotes had an increased odds ratio of 9.2 (CI: 4.50 - 21.6), with reported significance of p < 0.0001.[PMID 18559567]
