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rs2242480

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 normal
(C;T) carrier of one CYP3A4*_20239G>A allele
(T;T) CYP3A4*_20239G>A homozygote
ReferenceGRCh38 38.1/141
Chromosome7
Position99763843
GeneCYP3A4
is asnp
is mentioned by
dbSNPrs2242480
ebirs2242480
HLIrs2242480
Exacrs2242480
Varsomers2242480
Maprs2242480
PheGenIrs2242480
hapmaprs2242480
1000 genomesrs2242480
hgdprs2242480
ensemblrs2242480
gopubmedrs2242480
geneviewrs2242480
scholarrs2242480
googlers2242480
pharmgkbrs2242480
gwascentralrs2242480
openSNPrs2242480
23andMers2242480
23andMe allrs2242480
SNP Nexus

SNPshotrs2242480
SNPdbers2242480
MSV3drs2242480
GWAS Ctlgrs2242480
GMAF0.3338
Max Magnitude0
? (C;C) (C;T) (T;T) 28
rs2242480 is a SNP in the CYP3A4 gene.

The rs2242480(T) allele defines the CYP3A4*_20239G>A variant.


[PMID 21692828OA-icon.png] The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors


[PMID 21902501] Genetic polymorphisms in CYP3A4 are associated with withdrawal symptoms and adverse reactions in methadone maintenance patients


[PMID 17615053OA-icon.png] Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk.


[PMID 18163429OA-icon.png] Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: the Flint Men's Health Study.


[PMID 18504423OA-icon.png] Polymorphisms in inflammation-related genes are associated with susceptibility to major depression and antidepressant response.


[PMID 18825162OA-icon.png] Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans.


[PMID 21071160] Analysis of 50 SNPs in CYP2D6, CYP2C19, CYP2C9, CYP3A4 and CYP1A2 by MALDI-TOF mass spectrometry in Chinese Han population.


[PMID 21199372] A functional polymorphism in the CYP3A4 gene is associated with increased risk of coronary heart disease in the Chinese Han population.


[PMID 22178823] [Distribution of variant alleles association with warfarin pharmacokinetics and pharmacodynamics in the Han population in China].


[PMID 22583563OA-icon.png] Genetic and environmental predictors of serum 25-hydroxyvitamin D concentrations among middle-aged and elderly Chinese in Singapore.


[PMID 25217544] Fatal Methadone Toxicity: Potential Role of CYP3A4 Genetic Polymorphism


[PMID 27257124] CYP gene family variants as a potential risk factors in drug addiction in Han Chinese.