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rs2297518

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A)
Make rs2297518(A;G)
Make rs2297518(G;G)
ReferenceGRCh38 38.1/141
Chromosome17
Position27769571
GeneNOS2
is asnp
is mentioned by
dbSNPrs2297518
ebirs2297518
HLIrs2297518
Exacrs2297518
Varsomers2297518
Maprs2297518
PheGenIrs2297518
hapmaprs2297518
1000 genomesrs2297518
hgdprs2297518
ensemblrs2297518
gopubmedrs2297518
geneviewrs2297518
scholarrs2297518
googlers2297518
pharmgkbrs2297518
gwascentralrs2297518
openSNPrs2297518
23andMers2297518
23andMe allrs2297518
SNP Nexus

SNPshotrs2297518
SNPdbers2297518
MSV3drs2297518
GWAS Ctlgrs2297518
GMAF0.1726
Max Magnitude
? (A;A) (A;G) (G;G) 28
[PMID 20565800OA-icon.png] Gastric cancer is associated with NOS2 -954G/C polymorphism and environmental factors in a Brazilian population

[PMID 20581851OA-icon.png] Exploring epistatic relationships of NO biosynthesis pathway genes in susceptibility to CHD


[PMID 21716319] Maternal iNOS genetic polymorphisms and hypertensive disorders of pregnancy


[PMID 21963893OA-icon.png] Polymorphisms of genes in nitric oxide-forming pathway associated with ischemic stroke in Chinese Han population


[PMID 22234503] Inducible nitric oxide synthase haplotype associated with migraine and aura

[PMID 16543247] Polymorphisms in oxidative stress genes and risk for non-Hodgkin lymphoma.

[PMID 16642433OA-icon.png] Polymorphism in maternal LRP8 gene is associated with fetal growth.

[PMID 17355643OA-icon.png] Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population.

[PMID 17601350OA-icon.png] A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.

[PMID 17955236] Influence of the inducible nitric oxide synthase gene (NOS2A) on inflammatory bowel disease susceptibility.

[PMID 18663495OA-icon.png] Nitric oxide synthase genes and their interactions with environmental factors in Parkinson's disease.

[PMID 18667089OA-icon.png] A method for detecting epistasis in genome-wide studies using case-control multi-locus association analysis.

[PMID 18676870OA-icon.png] Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.

[PMID 19168583OA-icon.png] Nitric oxide synthase gene polymorphisms and prostate cancer risk.

[PMID 19309520OA-icon.png] Nitric oxide synthase 2A (NOS2A) polymorphisms are not associated with invasive pneumococcal disease.

[PMID 20416077OA-icon.png] Identification of type 2 diabetes-associated combination of SNPs using support vector machine.

[PMID 20562898OA-icon.png] Nitric oxide synthase 2 gene polymorphisms are associated with prostatic volume in Korean men with benign prostatic hyperplasia.

[PMID 20811626OA-icon.png] Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.

[PMID 21385363OA-icon.png] Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study.

[PMID 21481004] Association between recurrent aphthous stomatitis and inheritance of a single-nucleotide polymorphism of the NOS2 gene encoding inducible nitric oxide synthase.

[PMID 21612325] Ser608Leu polymorphisms in the nitric oxide synthase-2 gene may influence urinary bladder cancer pathogenesis.


GET Evidence
NOS2-S608L
aa_change Ser608Leu
aa_change_short S608L
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.168619
summary



[PMID 23192595] A non-synonymous SNP in the NOS2 associated with septic shock in patients with sepsis in Chinese populations


[PMID 23572278] Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans


[PMID 24114042] Nitric Oxide Synthase Gene Polymorphisms in Functional Dyspepsia


[PMID 24430113OA-icon.png] Higher activity of the inducible nitric oxide synthase contributes to very early onset inflammatory bowel disease


[PMID 22865486] Interaction among nitric oxide (NO)-related genes in migraine susceptibility.


[PMID 24746566] Genetic variants in inducible nitric oxide synthase gene are associated with the risk of radiation-induced lung injury in lung cancer patients receiving definitive thoracic radiation


[PMID 26579803OA-icon.png] Functional Inducible Nitric Oxide Synthase Gene Variants Associate With Hypertension: A Case-Control Study in a Finnish Population-The TAMRISK Study