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rs2352028

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0
(C;T) 2
(T;T) 2 Increased risk of lung cancer in non-smokers and never smokers
ReferenceGRCh38 38.1/141
Chromosome13
Position91792975
GeneGPC5
is asnp
is mentioned by
dbSNPrs2352028
ebirs2352028
HLIrs2352028
Exacrs2352028
Varsomers2352028
Maprs2352028
PheGenIrs2352028
hapmaprs2352028
1000 genomesrs2352028
hgdprs2352028
ensemblrs2352028
gopubmedrs2352028
geneviewrs2352028
scholarrs2352028
googlers2352028
pharmgkbrs2352028
gwascentralrs2352028
openSNPrs2352028
23andMers2352028
23andMe allrs2352028
SNP Nexus

SNPshotrs2352028
SNPdbers2352028
MSV3drs2352028
GWAS Ctlgrs2352028
GMAF0.3636
Max Magnitude2
? (C;C) (C;T) (T;T) 28
news increased risk of lung cancer in non smokers. Analysis showed that the presence of this variant significantly increased the risk of a never smoker having lung cancer by 1.46 times (odds ratio 1.46, 95% confidence interval 1.26 to 1.70).


[PMID 20304703OA-icon.png] Genetic variants and risk of lung cancer in never smokers: a genome-wide association study



[PMID 22236185] GPC5 rs2352028 Polymorphism and Risk of Lung Cancer in Han Chinese


GET Evidence
rs2352028
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.40625
summary



[PMID 24456789] Variants in the 5'-upstream region of GPC5 confer risk of lung cancer in never smokers


[PMID 23297363OA-icon.png] Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot.