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rs2953145

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 0 normal
(C;G) 1.8x risk
(G;G) 2.1x risk
ReferenceGRCh38 38.1/141
Chromosome2
Position240576179
GeneRNPEPL1
is asnp
is mentioned by
dbSNPrs2953145
ebirs2953145
HLIrs2953145
Exacrs2953145
Varsomers2953145
Maprs2953145
PheGenIrs2953145
hapmaprs2953145
1000 genomesrs2953145
hgdprs2953145
ensemblrs2953145
gopubmedrs2953145
geneviewrs2953145
scholarrs2953145
googlers2953145
pharmgkbrs2953145
gwascentralrs2953145
openSNPrs2953145
23andMers2953145
23andMe allrs2953145
SNP Nexus

SNPshotrs2953145
SNPdbers2953145
MSV3drs2953145
GWAS Ctlgrs2953145
GMAF0.1437
Max Magnitude0
? (C;C) (C;G) (G;G) 28
rs2953145 has been reported in a large study to be associated with bipolar disorder.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.84 (CI 1.31-2.58), and for homozygotes, 2.14 (CI 1.53-2.98). [PMID 17554300OA-icon.png]

GWAS
SNP rs2953145
PubMedID [PMID 17554300OA-icon.png]
Condition Bipolar disorder
Gene NR
Risk Allele C
pValue 7.00E-006
OR 1.84
95% CI 1.31-2.58



GET Evidence
rs2953145
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.804688
summary