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rs3213619

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(T;T) 0 common in complete genomics
Make rs3213619(C;C)
Make rs3213619(C;T)
ReferenceGRCh38 38.1/141
Chromosome7
Position87600877
GeneABCB1
is asnp
is mentioned by
dbSNPrs3213619
ebirs3213619
HLIrs3213619
Exacrs3213619
Varsomers3213619
Maprs3213619
PheGenIrs3213619
hapmaprs3213619
1000 genomesrs3213619
hgdprs3213619
ensemblrs3213619
gopubmedrs3213619
geneviewrs3213619
scholarrs3213619
googlers3213619
pharmgkbrs3213619
gwascentralrs3213619
openSNPrs3213619
23andMers3213619
23andMe allrs3213619
SNP Nexus

SNPshotrs3213619
SNPdbers3213619
MSV3drs3213619
GWAS Ctlgrs3213619
GMAF0.06015
Max Magnitude0
? (C;C) (C;T) (T;T) 28


[PMID 17146660] Association of MDR1 genotypes with susceptibility to colorectal cancer in older non-smokers.


[PMID 17622943] Comparative and evolutionary pharmacogenetics of ABCB1: complex signatures of positive selection on coding and regulatory regions.


[PMID 18424454OA-icon.png] ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence.


[PMID 20354687OA-icon.png] Explaining variability in ciclosporin exposure in adult kidney transplant recipients.


[PMID 20389299OA-icon.png] Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism.


[PMID 22306099] Association between the functional polymorphism (C3435T) of the gene encoding P-glycoprotein (ABCB1) and major depressive disorder in the Japanese population.


GET Evidence
rs3213619
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.0390625
summary



[PMID 24572589] Novel and functional ABCB1 gene variant in sporadic Parkinson's disease


[PMID 24599932] Replication of Genetic Polymorphisms Reported to be Associated with Taxane-Related Sensory Neuropathy in Early Breast Cancer Patients treated with Paclitaxel