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rs3747517

From SNPedia

Orientationminus
Stabilizedminus
Make rs3747517(A;A)
Make rs3747517(A;G)
Make rs3747517(G;G)
ReferenceGRCh38 38.1/141
Chromosome2
Position162272314
GeneIFIH1
is asnp
is mentioned by
dbSNPrs3747517
ebirs3747517
HLIrs3747517
Exacrs3747517
Varsomers3747517
Maprs3747517
PheGenIrs3747517
hapmaprs3747517
1000 genomesrs3747517
hgdprs3747517
ensemblrs3747517
gopubmedrs3747517
geneviewrs3747517
scholarrs3747517
googlers3747517
pharmgkbrs3747517
gwascentralrs3747517
openSNPrs3747517
23andMers3747517
23andMe allrs3747517
SNP Nexus

SNPshotrs3747517
SNPdbers3747517
MSV3drs3747517
GWAS Ctlgrs3747517
GMAF0.3912
Max Magnitude
? (A;A) (A;G) (G;G) 28

[PMID 19450885] Multiple sclerosis and polymorphisms of innate pattern recognition receptors TLR1-10, NOD1-2, DDX58, and IFIH1


[PMID 18071670] The association between the IFIH1 locus and type 1 diabetes.


[PMID 18927125OA-icon.png] IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells.


[PMID 19264985OA-icon.png] Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes.


[PMID 19374514OA-icon.png] Expression and alternative splicing of folate pathway genes in HapMap lymphoblastoid cell lines.


[PMID 19956101OA-icon.png] Overview of the Rapid Response data.


[PMID 19956106OA-icon.png] Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.


[PMID 19956109OA-icon.png] The Type I Diabetes Genetics Consortium 'Rapid Response' family-based candidate gene study: strategy, genes selection, and main outcome.


[PMID 22053898] IFIH1 gene polymorphisms in type 1 diabetes: genetic association analysis and genotype-phenotype correlation in Chinese Han population.


[PMID 22152027] Genetic variants in IFIH1 play opposite roles in the pathogenesis of psoriasis and chronic periodontitis.


GET Evidence
IFIH1-H843R
aa_change His843Arg
aa_change_short H843R
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.691764
summary



[PMID 22789000] Polymorphisms in the interferon-induced helicase (IFIH1) locus and susceptibility to Addison's disease


[PMID 23535865] Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility


[PMID 24960033] Association of innate immune IFIH1 gene polymorphisms with dilated cardiomyopathy in a Chinese population


[PMID 25337792] Genetic association study of TNFAIP3, IFIH1, IRF5 polymorphisms with polymyositis/dermatomyositis in Chinese Han population


[PMID 25515714] Cumulative effect of IFIH1 variants and increased gene expression associated with type 1 diabetes