Have questions? Visit https://www.reddit.com/r/SNPedia

rs3803300

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(G;G) 0
Make rs3803300(A;A)
Make rs3803300(A;G)
ReferenceGRCh38 38.1/141
Chromosome14
Position104803442
GeneZBTB42
is asnp
is mentioned by
dbSNPrs3803300
ebirs3803300
HLIrs3803300
Exacrs3803300
Varsomers3803300
Maprs3803300
PheGenIrs3803300
hapmaprs3803300
1000 genomesrs3803300
hgdprs3803300
ensemblrs3803300
gopubmedrs3803300
geneviewrs3803300
scholarrs3803300
googlers3803300
pharmgkbrs3803300
gwascentralrs3803300
openSNPrs3803300
23andMers3803300
23andMe allrs3803300
SNP Nexus

SNPshotrs3803300
SNPdbers3803300
MSV3drs3803300
GWAS Ctlgrs3803300
GMAF0.2902
Max Magnitude0
[PMID 17915974] G allele associated with schizophrenia

[PMID 18855532] among 120 (likely Japanese) first-episode neuroleptic-naive schizophrenics treated with risperidone genotyped for 30 variants in misc. dopamine and serotonin (receptors and otherwise) two SNPs in DRD2 (rs1799989 and rs1800497) and two SNPs in AKT1 (rs3803300 and rs2494732) were significant predictors of treatment response to risperidone

The ancestral allele is G in the dbSNP database.



[PMID 22277669] Genetic overlap between schizophrenia and bipolar disorder: A study with AKT1 gene variants and clinical phenotypes


[PMID 16260726OA-icon.png] Detection of functional single-nucleotide polymorphisms that affect apoptosis.


[PMID 16395129] Absence of significant associations between four AKT1 SNP markers and schizophrenia in the Taiwanese population.


[PMID 17464696] AKT1 and neurocognition in schizophrenia.


[PMID 18715757OA-icon.png] Genetic associations with schizophrenia: meta-analyses of 12 candidate genes.


[PMID 19911060OA-icon.png] Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpoint.


[PMID 19931325] No association between AKT1 polymorphism and schizophrenia: a case-control study in a Korean population and a meta-analysis.


[PMID 20046382OA-icon.png] AKT1 Gene Polymorphisms and Obstetric Complications in the Patients with Schizophrenia.


[PMID 21842521] AKT1 polymorphisms and survival of early stage non-small cell lung cancer.


GET Evidence
rs3803300
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.734375
summary



[PMID 25060489] Genetic variants in AKT1 gene were associated with risk and survival of OSCC in Chinese Han Population


[PMID 26988277] Genetic Association of Curative and Adverse Reactions to Tyrosine Kinase Inhibitors in Chinese advanced Non-Small Cell Lung Cancer patients.


[PMID 27305091] Genetic Association of TCF4 and AKT1 Gene Variants with the Age at Onset of Schizophrenia.