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rs3843763

From SNPedia

lower HDL cholesterol
Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 1.6 Normal (higher) HDL "Good" Cholesterol.
(C;T) 1.5 Slightly lower HDL ("Good") Cholesterol.
(T;T) 1.9 Slightly lower HDL ("Good") Cholesterol.
ReferenceGRCh38 38.1/141
Chromosome20
Position45919554
GenePLTP
is asnp
is mentioned by
dbSNPrs3843763
ebirs3843763
HLIrs3843763
Exacrs3843763
Varsomers3843763
Maprs3843763
PheGenIrs3843763
hapmaprs3843763
1000 genomesrs3843763
hgdprs3843763
ensemblrs3843763
gopubmedrs3843763
geneviewrs3843763
scholarrs3843763
googlers3843763
pharmgkbrs3843763
gwascentralrs3843763
openSNPrs3843763
23andMers3843763
23andMe allrs3843763
SNP Nexus

SNPshotrs3843763
SNPdbers3843763
MSV3drs3843763
GWAS Ctlgrs3843763
GMAF0.3182
Max Magnitude1.9
The (T) allele of rs3843763 was associated with risk for lower high-density lipoprotein (HDL) cholesterol plasma levels in 3 independent population samples, including both Caucasians and African-Americans.[PMID 17952847OA-icon.png]
OMIM172425
DescPHOSPHOLIPID TRANSFER PROTEIN; PLTP
Variant
Relatedalso


OMIM172425
Desc
Variant0001
Relatedalso


GET Evidence
rs3843763
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.320312
summary



ClinVar
Risk rs3843763(T;T)
Alt rs3843763(T;T)
Reference rs3843763(C;C)
Significance Other
Disease High density lipoprotein cholesterol level quantitative trait locus 9
Variation info
Gene
CLNDBN High density lipoprotein cholesterol level quantitative trait locus 9
Reversed 0
HGVS NC_000020.10:g.44548193C>T
CLNSRC OMIM Allelic Variant
CLNACC RCV000014604.2,